Gross gaming revenue from sports betting in September was 15.5% higher than the previous monthly-high of $124.1m, which was set in the first month of legal wagering in January this year.
The September total was also 43.9% higher than $99.6m in August.
In terms of spending, handle for the month amounted at $1.26bn, up 44.1% from $872.2m in August and was the highest monthly total since May.
Flutter Entertainment-owned FanDuel remained comfortably the market leader with $65.7m in GGR from $499.8m in player bets during the month.
DraftKings was the closest challenger with $44.9m in GGR from a $422.2m handle, followed by Caesars Sportsbook, which posted $18.6m in GGR and a $163.2m handle.
BetMGM generated $8.6m in GGR from $95.7m in wagers in September, while Rush Street Interactive posted $3.7m in GGR off $34.9m and PointsBet $1.7m off $23.9m.
Wynn Interactive was next with GGR of $685,306 from a $9.4m handle, then Resorts World with $394,796 from $6.4m, and finally BallyBet with $144,756 off $1.3m.