Okala, whose highest ATP ranking was 338, was found guilty of seven match fixing charges, while Lescure, who had a highest ATP ranking of 487, was found guilty of eight charges.
The ITIA also said the players have both been part of wider law enforcement investigations in France and Belgium.
The sanctions mean both players are permanently prohibited from playing in or attending any tennis event sanctioned by the governing bodies of tennis. Okala was also issued with a $15,000 (£12,220/€14,214) fine and Lescure was fined $40,000.
In the case of Okala, the player was found guilty of several breaches of the Tennis Anti-Corruption Programme (TACP), including three counts of section D.2.a.i of the 2014, 2016, 2017, and 2018 TACPs. These sections related to the requirement for a player to report any match-fixing approaches to the ITIA.
Okala was also guilty of two counts of section D.1.d of the 2017 TACP, whereby no covered person shall contrive or attempt to contrive the outcome or any other aspect of any event.
In addition, it was ruled Okala was guilty of two counts of section D.1.e of the 2017 TACP, which states covered persons must not solicit or facilitate any player to not use his or her best efforts in any event.
Turning to Lescure, he was found guilty of counts of section D.1.d of the 2014, 2016, 2017 and 2018 TACPs, in relation to influencing the outcome of other aspect of an event.
In addition, like Okala, Lescure was ruled to be guilty of two counts of section D.1.e of the TACP from 2014, 2016, 2017 and 2018 TACPs. The cases were ruled on by independent anti-corruption hearing officer Charles Hollander KC.