The total was a 40% increase over 2020, while it was 13% more than in 2019, before the impact of Covid-19.
As well as the revenue total reaching record heights, the year-on-year increase was also the largest on record.
However, National Indian Gaming Commission (NIGC) chairman Sequoyah Simermeyer noted that many tribes still had a difficult year, and said the organisation would continue to support tribes that have struggled.