Wagering handle for the month amounted to $43.1m (£38.3m/€44.0m), down from $54.8m in September 2021, but more than double the $21.2m spent by consumers in August of this year.
However, despite the decline in spending, revenue was level year-on-year $8.8m, with this figure also 225.9% higher than $2.7m in August.
Coastal casinos remained the most popular venues to place bets on sports in Mississippi, with players wagering a total of $28.1m and the casinos turning a revenue of $5.5m.
Handle for central casinos was $8.2m, with revenue at $1.8m, while spending at northern casinos totalled $6.9m and revenue $1.6m.
Football overtook baseball to become the sport of choice among players, with $16.5m bet at coastal casinos, $3.1m at central casinos and $4.4m at northern casinos.
Win percentage for the month was 20.4%, an increase from 16.1% in September last year.