The licence will enable Casino de Spa to offer online games of chance over the internet to players in the Netherlands.
The new permit came into effect on 2 February and will be valid for a period of five years, to February 2027.
Casino de Spa will operate in the Netherlands via its Casino777.be online brand.
The operator becomes the 12th business to secure an igaming licence in the Netherlands since the country launched its regulated online gambling market on 1 October last year.
The market went live with an initial 10 operators, with the KSA having issued licences to bet365, UK-based bingo operator Tombola and Malta- and Estonia-licensed Play North Ltd are among the brands cleared to launch, alongside Dutch land-based operator Holland Casino NV and state lottery Nederlandse Loterij with its TOTO Online betting brand.
The Janshen Hahnraths Group with FPO Nederland, Italy-based Betent, Belgian brand Bingoal, NSUS Malta, which runs the GGPoker.eu brand and sports media and betting business LiveScore Malta also held licences on opening day.
JOI Gaming, a division of Dutch land-based casino operator JVH Gaming & Entertainment Group, also secured an online gambling licence in the country in November.