The launch will enable customers to place pre-game, in-play, futures and parlay wagers from any mobile device while on site at the casino in Biloxi.
The app is available for download across Mississippi but geolocation technology limits users to placing bets only when on site at approved locations.
Consumers can also wager via the BetMGM app at the Gold Strike Casino Resort in Tunica, after the operator launched at the facility in September.